Stereological aspects of pathology of gliomas: volume density of nuclei and volume corrected mitotic index
Dariusz Adamek,
Department of Neuropathology, Institute of Neurology, Jagiellonian University, Collegium Medicum Botaniczna 3, 31-503 Kraków, Poland
Józef Kałuża,
Department of Neuropathology, Institute of Neurology, Jagiellonian University, Collegium Medicum Botaniczna 3, 31-503 Kraków, Poland
Abstract
There is still need to develop objective and reproducible methods of histopathological assessment of gliomas. In this 2-D study we tried to apply some stereological methods i.e. volume density of nuclei and volume corrected mitotic index in evaluation of gliomas. Volume density of nuclei measured in histological slides of cerebral gliomas seems to be a better estimator of malignancy than the cellularity of the tumor. The morphometric analysis also points on the usefulness of volume corrected mitotic index as a more exact indicator of tumor cell proliferation than usual mitotic index.
Keywords : glioma, mitotic index, morphometry
Para citar este artículo
Dariusz Adamek & Józef Kałuża, «Stereological aspects of pathology of gliomas: volume density of nuclei and volume corrected mitotic index», Acta Stereologica [En ligne], Volume 12 (1993), Number 1 - Sep. 1993, 65-70 URL : https://popups.uliege.be/0351-580x/index.php?id=1404.