Stereologic analysis of muscle capillaries in Inclusion Body Myositis
Marcelino G. Reyes,
Department of Pathology, Mount Sinai Hospital, Chicago, Illinois USA 60608
Steven M. Malkin,
Department of Pathology, Mount Sinai Hospital, Chicago, Illinois USA 60608
Moris J. Danon,
Department of Neurology, University of Illinois Hospital, Chicago, Illinois USA 60608
Abstract
Muscle capillaries of plastic-embedded sections of biopsies of seven patients with Inclusion Body Myositis (IBM) and of seven control patients were quantitatively estimated by point and line intersection counting technics of stereology. Volume, surface and numerical densities of capillaries and numerical ratio of capillaries to muscle fibers of IBM did not differ from controls. In contrast, estimates from selected atrophic areas in the biopsies of six patients with IBM were significantly higher than estimates randomly obtained from the same biopsies. Our findings suggest that muscle capillary hypervascularity in IBM results from atrophy of muscle fibers.
Pour citer cet article
Marcelino G. Reyes, Steven M. Malkin & Moris J. Danon, «Stereologic analysis of muscle capillaries in Inclusion Body Myositis», Acta Stereologica [En ligne], Volume 2 (1983), Number 2 - Proceedings of the second symposium on morphometry in morphological diagnoses, september 7-9, 1983, Kuopio, Finland - Dec. 1983, 368-372 URL : https://popups.uliege.be/0351-580x/index.php?id=4237.