Morphological markers in cytology
Georg Burger,
Gesellschaft für Strahlen- und Umweltforschung, mbH, München, Institut für Strahlenschutz, Ingolstädter Landstraβe 1, 8042 Neuherberg, West-Germany
Karsten Rodenacker,
Gesellschaft für Strahlen- und Umweltforschung, mbH, München, Institut für Strahlenschutz, Ingolstädter Landstraβe 1, 8042 Neuherberg, West-Germany
Uta Jütting,
Gesellschaft für Strahlen- und Umweltforschung, mbH, München, Institut für Strahlenschutz, Ingolstädter Landstraβe 1, 8042 Neuherberg, West-Germany
Peter Gais,
Gesellschaft für Strahlen- und Umweltforschung, mbH, München, Institut für Strahlenschutz, Ingolstädter Landstraβe 1, 8042 Neuherberg, West-Germany
Ulrich Schenck,
Institut für Klinische Zytologie der TU-München, West-Germany
Abstract
Morphological markers in cytology concern cytometric features of diagnostic relevance. These may be global size or shape descriptors, global photometric features, such as mean or total extinction of cellular constituents, and finally features describing the fine structure of the chromatin distribution in the nuclei. The role of cellular morphological markers and their validity with respect to different cytological tasks, such as diagnosis of cervical intraepithelial lesions, tumor diagnosis or typing and prognostic grading of cancer was investigated in gynecological smears and fine needle aspirates of the thyroid and the breast.
In all cases it was evident that chromatin pattern features, which can only reasonably be derived by local resolutions at the physical limits of light microscopy, are more powerful than global karyometric or photometric features.
Keywords : breast, cervix, chromatin feature, morphological markers, thyroid
Pour citer cet article
Georg Burger, Karsten Rodenacker, Uta Jütting, Peter Gais & Ulrich Schenck, «Morphological markers in cytology», Acta Stereologica [En ligne], Volume 4 (1985), Number 2 - Proceedings of the fourth European symposium for stereology - Dec. 1985, 243-248 URL : https://popups.uliege.be/0351-580x/index.php?id=3265.
