Morphometric analysis of normal muscle biopsies: a statistical approach
Pierre Tankosic,
Service Commun d'Analyse d'Images, Laboratoire d'Histologie A, BP 184, 54505 Vandoeuvre-lès-Nancy Cedex, France
Catherine Marchal,
Service Commun d'Analyse d'Images, Laboratoire d'Histologie A, BP 184, 54505 Vandoeuvre-lès-Nancy Cedex, France
Jean Floquet,
Laboratoire d'Anatomie Pathologique B, BP 184, 54505 Vandoeuvre-lès-Nancy Cedex, France
Claude Burlet,
Service Commun d'Analyse d'Images, Laboratoire d'Histologie A, BP 184, 54505 Vandoeuvre-lès-Nancy Cedex, France
Abstract
With a Quantimet 720, an automated image analysis of muscle cross-sections has been developed, using the property of muscle tissue to display two main fibre types with the ATPase reaction. 14 parameters, including size, number and spatial, distribution, have been investigated on 53 biopsies of normal leg muscles. The data were tested in relation with sex and increasing age. Some trends are apparent which indicate a certain wide variability within the morphometric parameters concerning the normal muscle. A principal component analysis revealed 3 distinct groups of parameters. The most reliable ones are the type I/type II area ratio and the coefficient of variation of the fibre size.
Pour citer cet article
Pierre Tankosic, Catherine Marchal, Jean Floquet & Claude Burlet, «Morphometric analysis of normal muscle biopsies: a statistical approach», Acta Stereologica [En ligne], Volume 4 (1985), Number 1 - Nov. 1985, 33-46 URL : https://popups.uliege.be/0351-580x/index.php?id=2934.