- Startpagina tijdschrift
- Volume 12 (1993)
- Number 1 - Sep. 1993
- Stereological aspects of pathology of gliomas: volume density of nuclei and volume corrected mitotic index
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Stereological aspects of pathology of gliomas: volume density of nuclei and volume corrected mitotic index
Abstract
There is still need to develop objective and reproducible methods of histopathological assessment of gliomas. In this 2-D study we tried to apply some stereological methods i.e. volume density of nuclei and volume corrected mitotic index in evaluation of gliomas. Volume density of nuclei measured in histological slides of cerebral gliomas seems to be a better estimator of malignancy than the cellularity of the tumor. The morphometric analysis also points on the usefulness of volume corrected mitotic index as a more exact indicator of tumor cell proliferation than usual mitotic index.