Cyto- and histometry in histological sections of colon carcinoma: method

Karsten Rodenacker; Michaela Aubele; Georg Burger; Peter Gais; Uta Jütting; Wolfgang Gössner; Martin Oberholzer

Acta Stereologica

0351-580X

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Karsten Rodenacker, Michaela Aubele, Georg Burger, Peter Gais, Uta Jütting, Wolfgang Gössner & Martin Oberholzer

Cyto- and histometry in histological sections of colon carcinoma: method

(Volume 9 (1990) — Number 2 - Proceedings of the seventh workshop on quantitative image analysis - Freiburg 90 - Dec. 1990)

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AS_9_n2_197_ROD (5.0M)

Abstract

Histological sections from colon carcinoma were evaluated by quantitative TV-microscopy. As a first step the nuclear profiles were digitized, segmented and measured. Besides classical cytometrical parameters like several global textural features, the fine structure of eu- and heterochromatin distribution was measured in terms of arrangement and neighbourhood relationship.

The resulting features are related to corresponding pathological diagnosis. As an example it is shown, that the existence of metastases may be correlated with features of the nuclear chromatin distribution.

Keywords : cytometry, graph theory, histometry, image analysis

To cite this article

Karsten Rodenacker, Michaela Aubele, Georg Burger, Peter Gais, Uta Jütting, Wolfgang Gössner & Martin Oberholzer, «Cyto- and histometry in histological sections of colon carcinoma: method», Acta Stereologica [En ligne], Volume 9 (1990), Number 2 - Proceedings of the seventh workshop on quantitative image analysis - Freiburg 90 - Dec. 1990, 197-203 URL : https://popups.uliege.be/0351-580x/index.php?id=2880.