Acta Stereologica

0351-580X

 

depuis le 05 décembre 2013 :
Visualisation(s): 162 (2 ULiège)
Téléchargement(s): 26 (4 ULiège)
print        
Mathilde E. Boon & Lambrecht P. Kok

Morphometric evidence of a relation between human papilloma virus infection and cervical intraepithelial neoplasm

(Volume 4 (1985) — Number 2 - Proceedings of the fourth European symposium for stereology - Dec. 1985)
Article
Open Access

Document(s) associé(s)

Annexes

Abstract

We report a quantitative method applied to histological sections to ascertain the disturbances of cellular and nuclear maturation in cervical squamous epithelium. Using this method, we could postulate which changes can be attributed to carcinogenesis, and which to infection with Human Papilloma Virus. In the context of the problem distinguishing these two entities in a diagnostic setting, and because there are indications that Human Papilloma Virus is involved in cervical carcinogenesis, our observations might be of importance for both pathologists and epidemiologists. Our findings indicate that there is a morphological continuum ranging from purely viral induced changes to morphological features of neoplasia, and that during these events the viral related changes are suppressed.

Keywords : carcinogenesis, histomorphometry, Human Papilloma Virus, koilocytosis

Pour citer cet article

Mathilde E. Boon & Lambrecht P. Kok, «Morphometric evidence of a relation between human papilloma virus infection and cervical intraepithelial neoplasm», Acta Stereologica [En ligne], Volume 4 (1985), Number 2 - Proceedings of the fourth European symposium for stereology - Dec. 1985, 267-272 URL : https://popups.uliege.be/0351-580x/index.php?id=3293.

A propos de : Mathilde E. Boon

Leiden Cytology Laboratory, Leiden, The Netherlands

A propos de : Lambrecht P. Kok

Leiden Cytology Laboratory, Leiden, The Netherlands; Institute for Theoretical Physics, Groningen, The Netherlands