- Startpagina tijdschrift
- Volume 1 (1982)
- Number 2 - Stereology 82 - Sheffield - Dec. 1982
- The concept of 'neuromorphotaxis' based on a minimisation principle. A case for the critical analysis of biological variation
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The concept of 'neuromorphotaxis' based on a minimisation principle. A case for the critical analysis of biological variation
Abstract
The size distributions of populations of neuronal somata, dendrite internode branch lengths and synapse areas are presented. These all show a positive skew and in some cases this is pronounced.
Arguments are put forward to explain this consistent finding. In general the tendency of biological systems to optimise their size on a minimising principle will be a contributory factor. In particular the excitable elements of the central nervous system possess the additional feature that size controls their physiological sensitivity and this is advanced as a major factor in the evolution of the experimental findings. The estimation of the majority of these measurements is possible only by the use of stereological techniques.