Angiogenesis evaluated with a new complexity measure

Haymo Kurz; Jörg Wilting; Bodo Christ; Konrad Sandau

Acta Stereologica

0351-580X

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Haymo Kurz, Jörg Wilting, Bodo Christ & Konrad Sandau

Angiogenesis evaluated with a new complexity measure

(Volume 18 (1999) — Number 1 - May 1999)

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AS_18_n1_27_KUR.pdf (2.4M)

Abstract

Growth factor effects on blood vessel patterns were assessed with a fast and automated method that measures complexity (extended counting method: XCM; Sandau, 1996). XCM is a robust estimator of complexity not only in theory but also in practice: 1) it fulfills the quasi-maximum-property; 2) it shows reduced variance due to pattem translation and rotation; 3) it is less sensitive to image manipulations and thresholding. XCM is superior to traditional fractal analysis for detecting changes in vascular complexity following growth factor and control treatment.

Keywords : angiogenesis, avian embryo, blood vessel pattem, complexity, fractal, VEGF

To cite this article

Haymo Kurz, Jörg Wilting, Bodo Christ & Konrad Sandau, «Angiogenesis evaluated with a new complexity measure», Acta Stereologica [En ligne], Volume 18 (1999), Number 1 - May 1999, 27-32 URL : https://popups.uliege.be/0351-580x/index.php?id=62.