Morphometrical changes in follicles of the thyroid glands in chronic alcoholism

Milica Matavulj; Milan Kecman; Ljiljana Somer

Acta Stereologica

0351-580X

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Milica Matavulj, Milan Kecman & Ljiljana Somer

Morphometrical changes in follicles of the thyroid glands in chronic alcoholism

(Volume 11 (1992) — Number 2 - Dec. 1992)

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Abstract

The effect of chronic ethanol consumption on the structure of thyroid gland follicles was the subject of our studies. Mature male Wistar rats were given 15% ethanol solution ad libitum as the only liquid offered. The animals were sacrificed in three groups: one, three and six months after the beginning of alcohol ingestion. Stereological analysis showed a significant increase in the volume density of follicular epithelium /Vve/, its thickness /t/, index of activation of the thyroid gland /Ia=Vve/Vvc/, and significant reduction in volume density of colloid /Vvc/ in all the periods examined. These results suggest the possibility that long-term alcoholism can disturb the normal structure of the thyroid gland, besides its well-known effects on the peripheral metabolism of thyroid hormones.

Keywords : chronic ingestion of ethanol, stereology, thyroid gland

Para citar este artículo

Milica Matavulj, Milan Kecman & Ljiljana Somer, «Morphometrical changes in follicles of the thyroid glands in chronic alcoholism», Acta Stereologica [En ligne], Volume 11 (1992), Number 2 - Dec. 1992, 199-204 URL : https://popups.uliege.be/0351-580x/index.php?id=1941.